Gillen · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2021 · narrative review · n=?

Exercise-nutrient interactions for improved postprandial glycemic control and insulin sensitivity.

Cited 41 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review without systematic search or meta-analytic methodology

PubMed 34081875 · doi:10.1139/apnm-2021-0168 · record verified 2026-08-27

What was done

Narrative review evaluating postprandial glucose and insulin dysregulation in individuals with or at risk for type 2 diabetes. It examines the effects of acute and chronic exercise—including moderate-intensity continuous exercise, low-intensity walking, high-intensity interval training, and resistance training—alongside the influence of exercise timing relative to meals and post-exercise nutrition on glycemic control and insulin sensitivity.

What was found

The abstract reports no quantitative values or effect sizes. It qualitatively describes that both single exercise sessions and repeated training improve postprandial glycemic control and insulin excursions in populations with and without type 2 diabetes, and notes that these responses are modified by meal timing and post-exercise macronutrient intake.

Why it matters

Highlights how coordinating exercise modality, timing around meals, and nutritional intake can be leveraged to manage postprandial hyperglycemia and hyperinsulinemia in metabolic disease prevention and treatment.

Limits

As a narrative review, it lacks systematic search criteria, meta-analytic pooling, and risk-of-bias grading. The abstract provides no quantitative metrics, specific timing protocols, or population sample sizes.

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