Rodriguez-Giustiniani · European journal of sport science 2022 · narrative review · n=?

Fluid and electrolyte balance considerations for female athletes.

Cited 28 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review of physiological mechanisms and empirical literature

PubMed 34121620 · doi:10.1080/17461391.2021.1939428 · record verified 2026-08-29

What was done

This narrative review synthesized literature examining the independent and integrated effects of estrogen and progesterone fluctuations across the menstrual cycle on fluid and electrolyte balance, thermoregulation, and rehydration in exercising females.

What was found

The abstract reports no quantitative data. Mechanistically, estrogen influences the osmotic threshold for arginine vasopressin release and progesterone influences aldosterone production. However, these mechanisms do not translate to consistent differences in resting or exercise plasma volume changes, fluid retention, or electrolyte losses. Estrogen-dominant phases (late-follicular) promote heat dissipation while progesterone-dominant phases (mid-luteal) elevate basal body temperature, but neither consistently alters observed sweat rates, heat stress, or exercise dehydration. Post-exercise fluid retention does not differ significantly across menstrual cycle phases.

Why it matters

Standardized hydration guidelines do not need broad phase-specific adjustments for the average female athlete, though individual variation in hormone fluctuations may warrant targeted monitoring.

Limits

The abstract does not state the number of studies reviewed or search methodology. Findings reflect population averages, which may obscure effects in individuals experiencing extreme hormonal fluctuations, and interactions between estrogen and progesterone remain incompletely characterized.

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