Consensus report: Definition and interpretation of remission in type 2 diabetes.
Level 5 - mechanism / opinion, no new human data
Expert consensus statement establishing definitions without new human experimental or observational data.
PubMed 34460965 · doi:10.1111/dme.14669
What was done
An international expert group convened by the American Diabetes Association formulated standardized nomenclature, diagnostic criteria, and monitoring principles for the sustained normalization of blood glucose levels in people with type 2 diabetes.
What was found
The panel agreed on "remission" as the optimal descriptor and proposed an HbA1c <6.5% (48 mmol/mol) measured at least 3 months after cessation of all glucose-lowering pharmacotherapy as the standard diagnostic criterion. The panel also established suggestions for active monitoring and identified research gaps concerning remission predictors and long-term outcomes.
Why it matters
Standardizing the definition and diagnostic thresholds for type 2 diabetes remission establishes a consistent benchmark for clinical practice, observational registries, and intervention trials.
Limits
This report represents expert consensus rather than a primary clinical trial or systematic review. The abstract provides no primary empirical data, sample sizes, or quantitative risk-benefit estimates regarding long-term outcomes.
Cited by
- context Adopting healthy lifestyle habits such as diet, exercise, and proper sleep can reverse diabetes.