Greenberg · International journal of environmental research and public health 2021 · narrative review · n=?

Sugars and Sweet Taste: Addictive or Rewarding?

Cited 29 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review without systematic search or quantitative synthesis

PubMed 34574716 · doi:10.3390/ijerph18189791 · record verified 2026-08-31

What was done

This was a narrative review of selected literature examining whether sweet taste and sugar overconsumption represent true substance addiction or natural hedonic reward. The authors evaluated evidence covering neuroimaging (fMRI) methodologies linking food to drug addiction pathways, the effects of low-calorie sweeteners on total caloric intake, and behavioral and neurobiological distinctions between drug addiction and sweet taste palatability.

What was found

The abstract provides no quantitative data or specific numerical findings. The authors report that functional MRI data linking food and drug neural pathways suffer from reproducibility issues. They note population-level evidence indicating that sweet taste without calories (low-calorie sweeteners) does not increase total caloric intake. Based on their synthesis, the authors conclude that the neurobiology of palatability and reward is distinct from addiction, and that palatability rather than metabolic consequences drives sweet food reward.

Why it matters

The paper challenges the popular framing of sugar and sweet food overeating as a clinical addiction, proposing that conflating hedonic reward with addictive potential mischaracterizes the drivers of human overconsumption.

Limits

As a narrative review, the study relies on selective rather than systematic literature identification, introducing risk of selection bias. No primary empirical data, quantitative meta-analyses, or study counts are reported in the abstract. The conclusions represent conceptual and theoretical critique rather than direct experimental testing.

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