Reversal of Acquired Prosopagnosia Using Quantitative Electroencephalography-Guided Laser Therapy.
Level 4 - case-series / case-control
Single-subject case report
PubMed 34981964 · doi:10.1089/photob.2021.0048
What was done
The authors administered quantitative electroencephalography (qEEG)-guided transcranial laser therapy (qGLT) to a single subject presenting with acquired associative-type prosopagnosia (AAP), temporal lobe epilepsy (TLE), and mild cognitive impairment (MCI). Objective and subjective clinical outcomes and qEEG assessments were conducted post-treatment, at 1 month, and followed up for 1 year.
What was found
The abstract reports no numerical values, effect sizes, or standardized test scores. It describes objective and subjective improvement in AAP, TLE, and MCI, additional qEEG improvement at 1 month post-treatment, and no recurrence of AAP at 1-year follow-up.
Why it matters
Effective interventions for acquired prosopagnosia are sparse, making this preliminary case report a potential hypothesis generator for transcranial photobiomodulation research.
Limits
This is an uncontrolled single-patient case report (n = 1) lacking blinding, sham control, and quantitative data in the abstract. Causality cannot be confirmed, and findings in a patient with multiple co-occurring neurological conditions may not generalize.
Cited by
- supports Dr. Robert Hedaya published the first case report of cured acquired prosopagnosia treated with laser therapy.