Toptancı · Environmental science and pollution research international 2022 · Laboratory analytical migration study · n=35 cookware samples

Assessment of the migration of perfluorinated compounds and primary aromatic amines from PTFE-coated non-stick cookware marketed in Turkey.

Cited 13 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Bench-top analytical chemical study without human participants (Level 5 by non-clinical design analogy).

PubMed 35080719 · doi:10.1007/s11356-022-18783-1 · record verified 2026-08-31

What was done

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used to measure the migration of 2 perfluorinated compounds (PFCs) and 17 primary aromatic amines (PAAs) from 35 PTFE-coated non-stick cookware samples marketed in Turkey. The authors evaluated the effects of food simulant volume (200, 500, and 1000 mL), temperature, and consecutive repeated uses on the release of these compounds.

What was found

PFOA was detected in 6 of the 35 cookware samples, while the other tested PFC was not identified. Among PAAs, aniline was detected in all 35 samples and 4,4'-methylenedianiline (4,4'-MDA) was detected in 4 samples. Target compounds were identified in 200 mL and 500 mL simulant volumes, with concentrations declining as simulant volume increased. Migration peaked at higher temperatures and decreased over consecutive usage cycles. Exact numeric concentrations are not reported in the abstract.

Why it matters

This study shows that some PTFE-coated cookware items release detectable levels of PFOA and primary aromatic amines into food simulants, with release highest during early uses and at elevated temperatures.

Limits

The abstract does not report specific quantitative concentrations or compare levels against regulatory safety thresholds. Migration was tested using food simulants rather than real foods, the sample was limited to 35 cookware products from Turkey, and human biological exposure was not assessed.

Cited by