Wirz-Justice · Praxis 2022 · narrative review · n=?

CME: Light Therapy: Why, What, for Whom, How, and When (And a Postscript about Darkness).

Cited 35 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review and CME guidance without systematic review methodology or primary clinical data

PubMed 35105211 · doi:10.1024/1661-8157/a003821 · record verified 2026-08-31

What was done

Narrative review and continuing medical education (CME) overview summarizing clinical guidelines and literature on light therapy. The authors review circadian mechanisms linking light to sleep, mood, alertness, and cognition, and outline treatment protocols, device selection criteria, and clinical indications for seasonal affective disorder and related psychiatric and neurological conditions.

What was found

No quantitative trial results, effect sizes, or participant numbers are reported in the abstract. The authors specify clinical parameter recommendations: treatment dose of 10,000 lux, white light spectrum, 30 to 60 minutes exposure duration, and early morning timing, used as monotherapy or adjunctively with antidepressants or lithium.

Why it matters

It provides practical clinical dosing standards and device criteria for administering light therapy to patients with seasonal affective disorder and other circadian-related mood and sleep disturbances.

Limits

The abstract presents expert CME guidance rather than primary empirical data or a systematic review. Quantitative efficacy rates, statistical comparisons, and specific adverse event frequencies are not provided.

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