Sevoz-Couche · Neuroscience and biobehavioral reviews 2022 · narrative review · n=?

Heart rate variability and slow-paced breathing:when coherence meets resonance.

Cited 199 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review synthesizing physiological and neural mechanisms without systematic review methodology

PubMed 35167847 · doi:10.1016/j.neubiorev.2022.104576 · record verified 2026-08-28

What was done

This narrative review synthesizes literature on slow-paced breathing, focusing on the mechanisms linking resonance frequency breathing (~0.1 Hz) to cardiovascular, autonomic, and central nervous system effects.

What was found

The abstract reports no empirical data, sample sizes, or statistical metrics. Mechanistically, it describes that breathing at ~0.1 Hz aligns respiratory, blood pressure, and cardiac phases into temporal coherence, increasing cardiac oscillations, vagally-mediated heart rate variability, and baroreflex sensitivity. This coherence extends vagal afferent stimulation to interoceptive regions and couples with increased cerebral blood flow and oxygen delivery oscillations to trigger neural activations in limbic areas.

Why it matters

It outlines a unified physiological framework connecting peripheral autonomic synchronization during slow breathing to central interoceptive and limbic brain activation.

Limits

The paper is a narrative review with no primary data, quantitative synthesis, or systematic search methodology reported in the abstract. The central neural cascades described represent theoretical and mechanistic pathways rather than directly quantified clinical outcomes.

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