Krugliakova · Frontiers in neuroscience 2022 · Interventional physiological study · n=?

Boosting Recovery During Sleep by Means of Auditory Stimulation.

Cited 36 times in the scientific literature.

Level 2 - randomized trial

Experimental human physiological intervention study (specific randomization details not stated in abstract)

PubMed 35185455 · doi:10.3389/fnins.2022.755958 · record verified 2026-08-26

What was done

Phase-targeted auditory stimulation (PTAS) was administered during deep sleep to evaluate its effects on the overnight dynamics of slow-wave activity (SWA, 1–4 Hz EEG power) and subsequent attentional performance. The abstract does not specify participant numbers, inclusion criteria, control/sham conditions, or detailed experimental protocols.

What was found

The abstract reports no numerical values, effect sizes, or statistical metrics. It qualitatively reports that PTAS applied during deep sleep accelerated the decline of SWA across the night, and that this change was associated with an overnight improvement in attentional performance.

Why it matters

This study provides evidence that phase-targeted auditory stimulation can modulate the physiological trajectory of slow-wave sleep and correlate with behavioral gains, offering potential utility for non-pharmacological sleep enhancement.

Limits

The abstract omits key methodological details, including sample size, participant demographics, sham controls, and randomization. No quantitative findings are provided, and outcome assessment was limited to attentional performance without broader clinical or physiological endpoints.

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