Mavreas · Journal of orthodontics 2022 · narrative review with case reports · n=2

Rejuvenation of the ageing face and the role of orthodontics: Guidelines for management.

Cited 4 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review and expert opinion with two illustrative clinical cases

PubMed 35437070 · doi:10.1177/14653125221093390 · record verified 2026-08-29

What was done

The authors reviewed anatomical aging patterns of the midface, maxilla, mandible, overlying soft tissues, and smile. Based on these mechanisms, they formulated clinical guidelines for facial rejuvenation through orthodontic therapy and presented two late-adulthood clinical cases as examples.

What was found

The abstract reports no numerical outcome data or statistical comparisons. It qualitatively details age-related changes—including clockwise rotation and retrusion of the maxilla, loss of mandibular bone and alveolar height, thinning of the epidermis, collagen depletion, and fat atrophy—and asserts that orthodontic intervention can restore facial shape and soft-tissue support.

Why it matters

The paper outlines a framework for using orthodontic tooth and jaw repositioning to address facial aging structural changes before or alongside cosmetic surgery.

Limits

This is a narrative review and expert opinion supported only by two illustrative cases. It lacks randomized or controlled clinical trial data, objective quantitative outcome measures, and evaluation of adverse effects or long-term stability.

Cited by