Latash · Physical therapy research 2022 · narrative review · n=?

Recent Advances in the Neural Control of Movements: Lessons for Functional Recovery.

Cited 9 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review synthesizing theoretical motor control frameworks and clinical applications without systematic review methodology or new primary data

PubMed 35582118 · doi:10.1298/ptr.R0018 · record verified 2026-08-26

What was done

This review synthesized theoretical frameworks of movement control and coordination descending from Nikolai Bernstein's concepts. It evaluated the theory of neural control via spatial referent coordinates across hierarchical levels from motor units to the whole body, alongside multi-element synergies using the uncontrolled manifold hypothesis and the principle of motor abundance. The authors analyzed applications to neurological movement disorders including spasticity, Parkinson's disease, multiple-system atrophy, and stroke, as well as peripheral conditions such as osteoarthritis.

What was found

The abstract reports theoretical models rather than numerical data. Movement disorders are framed as an inability to use the full range of referent coordinates or an inability to maintain stability of salient variables in multi-element synergies prior to actions. For peripheral conditions like osteoarthritis, joint stiffening is described as a maladaptive strategy that can compromise walking stability.

Why it matters

This framework links theoretical motor control concepts with physical therapy, offering a model to interpret movement deficits and evaluate compensatory strategies during rehabilitation.

Limits

This is a narrative review lacking systematic search criteria, meta-analytic pooling, and primary empirical data. No participant sample sizes, statistical effect sizes, or clinical outcome measurements are reported in the abstract.

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