Schiess · JAMA neurology 2022 · expert consensus / policy statement · n=?

Six Action Steps to Address Global Disparities in Parkinson Disease: A World Health Organization Priority.

Cited 145 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Expert consensus and policy framework without original clinical trial or observational data.

PubMed 35816299 · doi:10.1001/jamaneurol.2022.1783 · record verified 2026-08-27

What was done

Following the 73rd World Health Assembly resolution to create an intersectoral global action plan on neurological disorders, the World Health Organization (WHO) Brain Health Unit convened an international, multidisciplinary, sex-balanced consultation workshop in April 2021. The group synthesized evidence on global disparities in Parkinson disease (PD)—contextualized by Global Burden of Disease data spanning 1990 to 2016 across 195 countries and territories—to delineate global priority action areas.

What was found

The abstract reports no new empirical data or quantitative effect sizes. It notes that the Global Burden of Disease study (1990–2016) established PD as the fastest-growing neurological disorder in terms of disability and mortality, with the majority of affected individuals residing in low- and middle-income countries with inadequate access to care and essential medicines. The consultation identified six action domains: (1) disease burden; (2) advocacy and awareness; (3) prevention and risk reduction; (4) diagnosis, treatment, and care; (5) caregiver support; and (6) research.

Why it matters

This framework aligns international health policy priorities to mitigate disparities in PD clinical services, drug availability, and caregiver resources, providing a structured blueprint for governments, donors, and health systems.

Limits

The abstract describes a consensus-derived policy communication rather than an empirical trial or epidemiological investigation; it contains no primary quantitative outcomes, cost-effectiveness analyses, or implementation metrics evaluating the recommended action steps.

Cited by