Nonoyama · Journal of intellectual disability research : JIDR 2022 · cross-sectional survey · n=604

Cross-sectional study of the factors associated with the number of teeth in middle-aged and older persons with intellectual disabilities.

Cited 4 times in the scientific literature.

Level 4 - case-series / case-control

Cross-sectional survey study

PubMed 35929423 · doi:10.1111/jir.12967 · record verified 2026-08-28

What was done

A cross-sectional questionnaire survey on oral health was administered to 604 individuals over 40 years of age with intellectual disabilities in Aichi Prefecture, Japan. Information was collected via proxy reports on disability diagnosis, disability severity, residence type, proxy-reported tooth count (categorized as ≥20, 10–19, or 0–9), regular dental check-ups, and tooth-brushing frequency. Multinomial logistic regression and linear regression models were used to analyze factors associated with tooth count.

What was found

Having 0–9 teeth (versus ≥20) was significantly associated with Down syndrome compared to intellectual disability alone (OR 3.17, 95% CI 1.09–9.23), not attending regular dental check-ups (OR 2.37, 95% CI 1.06–5.30), and brushing once daily compared with ≥3 times daily (OR 4.76, 95% CI 1.09–20.77). In multivariate linear regression, tooth count decreased by 0.42 teeth per year of age, was 0.74 higher in autism spectrum disorder, 0.93 lower in Down syndrome, and 2.12 lower among participants without regular dental check-ups.

Why it matters

The study highlights modifiable risk factors (regular check-ups and brushing frequency) and high-risk groups (such as individuals with Down syndrome) for tooth loss in aging adults with intellectual disabilities.

Limits

The cross-sectional design cannot establish causality. Tooth counts and oral health habits were proxy-reported rather than clinically verified by dental examinations, risking reporting bias. The sample was drawn from a single geographic prefecture.

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