Sandkühler · Depression and anxiety 2022 · Randomized controlled trial · n=62

100,000 lumens to treat seasonal affective disorder: A proof of concept RCT of Bright, whole-ROom, All-Day (BROAD) light therapy.

Cited 8 times in the scientific literature.

Level 2 - randomized trial

Individual randomized controlled trial

PubMed 35981135 · doi:10.1002/da.23281 · record verified 2026-08-29

What was done

Sixty-two patients with seasonal affective disorder (SAD) were randomized for 4 weeks to either whole-room bright light therapy (BROAD: very brightly illuminated home room for at least 6 hours per day) or standard care (30 minutes daily in front of a 10,000-lux light box). Feasibility was evaluated through recruitment, adherence, and adverse effects. SAD symptoms were measured at baseline, 2 weeks, and 4 weeks using the 29-item self-report Hamilton Depression Rating Scale for Seasonal Affective Disorders.

What was found

All 62 enrolled patients completed the 4-week follow-up with no significant adverse effects reported. Both intervention groups showed similar and substantial improvements in SAD symptoms, though the abstract reports no specific numerical scores, confidence intervals, or p-values. Exploratory analyses showed that higher illuminance (lux) within the BROAD group correlated with greater symptom reduction.

Why it matters

This proof-of-concept trial suggests ambient, whole-room bright LED lighting is a feasible alternative to traditional light boxes without requiring patients to remain stationary in front of a device for 30 minutes daily.

Limits

The abstract reports no numerical outcome data, standard deviations, or test statistics. The trial had a small sample size (n=62), short follow-up duration (4 weeks), relied on self-reported depression ratings, and participants could not be blinded to lighting interventions.

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