Barr · Journal of drugs in dermatology : JDD 2022 · narrative review · n=?

The Role of Hormone Therapy in Female Aesthetic Rejuvenation.

Cited 2 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review and expert opinion without systematic review methodology or primary data

PubMed 36074510 · doi:10.36849/JDD.6232 · record verified 2026-08-29

What was done

This narrative review summarizes the literature regarding the roles of estrogen, progesterone, testosterone, dehydroepiandrosterone (DHEA), and melatonin in female aesthetic changes associated with postmenopausal hormone decline, including skin aging, hair thinning, weight gain, and fat redistribution.

What was found

The abstract reports no quantitative data, effect sizes, or trial numbers. It presents the qualitative conclusion that hormone therapies may prevent or reverse age-related aesthetic changes and can be incorporated into dermatologic rejuvenation strategies.

Why it matters

It outlines how hormonal pathways are conceptualized in aesthetic dermatology for treating age-related skin and body changes in women.

Limits

As a narrative review, it lacks systematic search methodology, quantitative synthesis, and direct clinical trial data in the abstract. Safety profiles, specific dosing, contraindications, and long-term risk-benefit trade-offs are not quantified.

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