Neuhuber · Biological psychology 2022 · narrative review · n=?

Functional anatomy of the vagus system: How does the polyvagal theory comply?

Cited 43 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review evaluating anatomical concepts without new empirical human data

PubMed 36100134 · doi:10.1016/j.biopsycho.2022.108425 · record verified 2026-08-28

What was done

The authors reviewed the functional neuroanatomy of the vagus nerve and its central brainstem connections in the context of biopsychological frameworks, specifically discussing anatomical evidence relevant to polyvagal theory and heart rate variability metrics.

What was found

The abstract reports no quantitative data. Anatomically, vagal afferent targets include the spinal trigeminal and paratrigeminal nuclei alongside classical brainstem nuclei (dorsal motor nucleus, nucleus ambiguus, and nucleus tractus solitarii), and the nucleus tractus solitarii integrates both visceral and somatic afferent signals.

Why it matters

Recalling precise functional neuroanatomy provides an empirical benchmark to evaluate whether popular biopsychological concepts, such as polyvagal theory, align with established neural wiring.

Limits

The abstract describes a narrative theoretical review with no empirical human dataset, sample size, or systematic literature search methodology reported.

Cited by