Li · Critical reviews in food science and nutrition 2024 · Narrative review · n=?

Formation, immunomodulatory activities, and enhancement of glucosinolates and sulforaphane in broccoli sprouts: a review for maximizing the health benefits to human.

Cited 32 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review without systematic search methodology or quantitative synthesis

PubMed 36847125 · doi:10.1080/10408398.2023.2181311 · record verified 2026-08-30

What was done

Narrative review summarizing the biosynthesis pathways, immunomodulatory mechanisms, and agronomic or postharvest enhancement strategies (including genotype selection, physicochemical elicitors, biological elicitors, and storage conditions) for glucosinolates and sulforaphane in broccoli sprouts.

What was found

The abstract reports no quantitative data, statistics, or numerical effect sizes. It describes qualitatively that sulforaphane derived from glucoraphanin hydrolysis is associated with reduced inflammation, that glucosinolate profiles vary by plant genotype, and that specific inducers stimulate biosynthetic gene expression and enzyme activity to promote sulforaphane accumulation in sprouts.

Why it matters

Synthesizes agricultural, postharvest, and biochemical methods aimed at maximizing sulforaphane yield in broccoli sprouts for potential functional food applications.

Limits

This is a narrative review that provides no quantitative data, statistical metrics, or systematic search criteria in the abstract. Findings are derived largely from mechanistic, plant physiology, and preclinical literature rather than controlled human clinical trials.

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