Effects of time-restricted eating with different eating duration on anthropometrics and cardiometabolic health: A systematic review and meta-analysis.
Level 1 - systematic review of randomized trials
Systematic review and meta-analysis of randomized clinical trials
PubMed 37576544 · doi:10.4330/wjc.v15.i7.354
What was done
Authors conducted a systematic review and meta-analysis of clinical trials identified via Medline, Scopus, Web of Science, Academic Search Complete, and Cochrane Library databases to examine daily time-restricted eating (TRE) in adults with excessive weight and obesity-related metabolic diseases. Risk of bias was evaluated using the Cochrane RoB-2 tool. Evaluated outcomes included body weight, waist circumference, fat mass, lean body mass, fasting glucose, insulin, HbA1c, HOMA-IR, lipid profile, C-reactive protein, blood pressure, and heart rate, including subgroup analyses based on eating window duration.
What was found
In 15 included studies, TRE resulted in statistically significant reductions in body weight, waist circumference, fat mass, lean body mass, blood glucose, insulin, and triglycerides. No significant changes were observed for HbA1c, HOMA-IR, total cholesterol, LDL cholesterol, HDL cholesterol, heart rate, or systolic and diastolic blood pressure. Subgroup analyses showed significant variation in effects depending on the duration of the eating window. The abstract reports no numerical effect sizes, variance measures, or p-values.
Why it matters
This synthesis suggests that TRE improves certain anthropometric and glycemic measures in adults with metabolic risk, with outcomes dependent on the daily eating window. It also demonstrates that fat loss from TRE may be accompanied by unintended loss of lean body mass.
Limits
The abstract provides no numerical data, effect estimates, or confidence intervals. The total participant count is omitted. TRE failed to improve blood pressure or key cholesterol fractions, and the observed reduction in lean body mass represents a potential clinical limitation.
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