Zagkas · Advances in experimental medicine and biology 2023 · systematic review of controlled trials · n=16 studies (853 participants)

How Does Meditation Affect the Default Mode Network: A Systematic Review.

Cited 7 times in the scientific literature.

Level 1 - systematic review of randomized trials

Systematic review of 16 controlled trials

PubMed 37581797 · doi:10.1007/978-3-031-31986-0_22 · record verified 2026-08-26

What was done

Following PRISMA guidelines, investigators searched PubMed, Scopus, and Embase through June 2020 for studies evaluating the effect of meditation on the Default Mode Network (DMN). Across 306 identified articles, 16 controlled trials comprising 853 experienced and novice meditators across diverse traditions (Mindfulness, Samatha, Raja Yoga, Transcendental Meditation, Vipassana, and Theravada Insight meditation) were included.

What was found

The abstract provides no numerical data, effect sizes, or specific statistical values. It reports qualitatively that meditative interventions affect DMN operation and that differences exist in functional connectivity between networks.

Why it matters

This review collates controlled trial evidence on how different contemplative traditions modulate neural functional connectivity and default mode network activity.

Limits

No quantitative findings or specific directional connectivity metrics are provided in the abstract. The review combines heterogeneous meditation styles, does not specify whether trials were randomized, and only includes literature published through June 2020.

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