Krikorian · Nutrients 2023 · controlled trial · n=?

Early Intervention in Cognitive Aging with Strawberry Supplementation.

Cited 22 times in the scientific literature.

Level 2 - randomized trial

Individual controlled trial evaluating a 12-week dietary intervention.

PubMed 37892506 · doi:10.3390/nu15204431 · record verified 2026-08-28

What was done

Overweight middle-aged men and women with insulin resistance and subjective cognitive decline participated in a 12-week controlled trial evaluating daily administration of whole-fruit strawberry powder. Diet records confirmed adherence to abstinence from outside berry products.

What was found

Strawberry-treated participants showed diminished memory interference (p = 0.02; Cohen's f = 0.45) and reduced depressive symptoms (p = 0.04; Cohen's f = 0.39). No effect was observed on metabolic measures.

Why it matters

This study provides preliminary evidence that introducing strawberry supplementation in midlife may support cognitive function and mood in adults at risk for late-life dementia.

Limits

The sample size is not reported in the abstract. The 12-week duration is short, the dose of anthocyanins was noted as comparatively low, and the intervention produced no measurable effect on metabolic parameters.

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