Léonard · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2024 · retrospective case series · n=25

Surgical labyrinthectomy in the treatment of unilateral Meniere disease: a Belgian retrospective study.

Cited 4 times in the scientific literature.

Level 4 - case-series / case-control

Retrospective single-center case series without a control group

PubMed 37938372 · doi:10.1007/s00405-023-08293-2 · record verified 2026-08-28

What was done

A retrospective study evaluated 25 patients with disabling, drug-resistant unilateral Meniere's disease and non-functional hearing who underwent surgical labyrinthectomy performed by a single surgeon at University Hospital UCL Namur between 2009 and 2019. Subjective and objective measures before and after surgery, including Dizziness Handicap Inventory scores, were analyzed from medical records.

What was found

Dizziness Handicap Inventory scores showed a statistically significant improvement post-surgery (p < 0.01), and 81% of patients were satisfied with the outcome. No post-operative complications occurred. Fourteen patients had favorable subjective and clinical outcomes without requiring further vestibular workup. All 25 patients had total deafness on the operated side as expected, and 4 required multidisciplinary rehabilitation for persistent tinnitus. Absolute baseline and post-operative numerical score values were not reported in the abstract.

Why it matters

This study provides single-center evidence that surgical labyrinthectomy remains a safe and effective definitive option for vertigo control in patients with intractable unilateral Meniere's disease whose hearing is already non-functional.

Limits

The study is limited by its retrospective single-surgeon design, small sample size (n = 25), and lack of a control or comparator group. The abstract omits precise baseline and follow-up numerical score metrics, confidence intervals, and follow-up duration.

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