Don · The Annals of otology, rhinology, and laryngology 2024 · Retrospective cross-sectional study · n=211

Polysomnographic Characteristics of Sleep Architecture in Children With Obstructive Sleep Apnea.

Cited 12 times in the scientific literature.

Level 4 - case-series / case-control

Retrospective cross-sectional comparative study of clinical sleep records

PubMed 38450648 · doi:10.1177/00034894241232477 · record verified 2026-08-29

What was done

Overnight polysomnography (PSG) records of 211 children (median age 7.0 years, range 4–10 years) referred for suspected obstructive sleep apnea (OSA) were reviewed. Subjects were classified by apnea-hypopnea index (AHI) into OSA and non-OSA cohorts, and sleep architecture parameters were analyzed.

What was found

Compared to children without OSA, those with OSA showed: - Increased stage N1 sleep: 6.10 vs 2.9 (P < .001) - Decreased stage N2 sleep: 42.0 vs 49.7 (P < .001) - Decreased REM sleep: 14.0 vs 15.9 (P = .05) - No significant difference in stage N3 sleep: 33.60 vs 30.60 (P = .14) - Higher arousal index: 12.9 vs 8.2 (P < .001) - Reduced sleep efficiency: 83.90 vs 89.40 (P = .003) - Reduced total sleep time: 368.50 vs 387.25 (P = .001) - Increased wake after sleep onset: reported as 40.1 ± 35.59 vs 28.66 ± 24.14 (P = .007) and 29.00 vs 20.50 (P = .011)

Why it matters

Clarifies pediatric OSA sleep architecture, demonstrating that while airway obstruction induces sleep fragmentation and shifts sleep into lighter stages, children preserve stage N3 deep sleep unlike adult OSA patients.

Limits

Retrospective analysis limited to referred patients whose comparison group also had suspected sleep-disordered breathing rather than healthy community controls. Specific AHI diagnostic thresholds, OSA severity subgroups, and potential confounding variables such as obesity or medications were not reported in the abstract.

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