Revelo Herrera · Cureus 2024 · systematic review · n=17 studies

The Effect of Aerobic Exercise in Neuroplasticity, Learning, and Cognition: A Systematic Review.

Cited 28 times in the scientific literature.

Level 1 - systematic review of randomized trials

Systematic review of 17 studies evaluating the effects of aerobic exercise

PubMed 38476815 · doi:10.7759/cureus.54021 · record verified 2026-08-29

What was done

This systematic review examined the association between physical activity, neuroplasticity, and cognition. The authors searched PubMed, Scopus, and the Virtual Health Library, retrieving 9,935 initial records. After applying screening filters and predefined eligibility criteria, 17 articles assessing the effects of aerobic exercise on neuroplasticity were included.

What was found

The abstract reports no numerical values, effect sizes, or statistical metrics. It describes qualitative findings that aerobic exercise across intensities—particularly high intensity—influences cortical excitability, induces direct cortical and structural changes, and improves cognition in diverse age groups with and without brain disease.

Why it matters

The review summarizes evidence supporting aerobic exercise as a modulator of structural and functional neuroplasticity linked to cognitive enhancement.

Limits

The abstract does not report quantitative data, effect sizes, or meta-analytic results. Specific study designs, participant sample sizes, exercise parameters, and neuroimaging or neurophysiological outcome measures of the 17 included studies are not detailed.

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