Odontogenic Maxillary Sinusitis Microbiology Compared With Chronic Rhinosinusitis: A Meta-Analysis.
Level 3 - non-randomized controlled study
Systematic review and meta-analysis of observational cross-sectional studies
PubMed 38881270 · doi:10.1177/19458924241259333
What was done
A systematic review and meta-analysis compared the microbiological profiles of odontogenic maxillary sinusitis (OMS), chronic rhinosinusitis (CRS), and normal sinuses. PubMed and CNKI databases were searched from inception through July 2023. A random-effects model was used to calculate pooled prevalence estimates of identified bacterial species and genera.
What was found
Seventeen studies were included, providing 191 OMS samples from 6 studies, 610 CRS samples from 12 studies, and 92 normal sinus samples from 4 studies. Fusobacterium was the only genus with a statistically significantly higher prevalence in OMS compared to CRS, though exact numerical prevalence values, odds ratios, and p-values were not reported in the abstract. Staphylococcus aureus was more prevalent in CRS than in OMS. Prevalence of Peptostreptococcus and Prevotella was generally higher in OMS compared to CRS, but the differences did not reach statistical significance.
Why it matters
This review identifies Fusobacterium enrichment as a potential microbiological marker distinguishing odontogenic maxillary sinusitis from chronic rhinosinusitis, which may inform targeted antimicrobial choices and differential diagnosis.
Limits
The abstract omits all numerical effect sizes, prevalence percentages, confidence intervals, and p-values. The total OMS sample size is small with only 191 samples across 6 studies, search sources were limited to two databases, and primary studies likely varied in microbiological sampling and detection methods.
Cited by
- context Chronic sinus infections are often caused by the same bacteria found in periodontal disease pockets.