Hurst · Deutsches Arzteblatt international 2024 · systematic review and meta-analysis of observational studies · n=12 studies

Daylight Saving Time Transitions and Risk of Heart Attack.

Cited 6 times in the scientific literature.

Level 3 - non-randomized controlled study

Systematic review and meta-analysis of observational studies

PubMed 38888468 · doi:10.3238/arztebl.m2024.0078 · record verified 2026-08-30

What was done

Authors conducted a systematic review and meta-analysis across eight databases through September 2023 examining acute myocardial infarction (AMI) rates in the first few weeks following daylight saving time (DST) transitions. Study quality was evaluated using the Newcastle-Ottawa Scale, and meta-regressions and sensitivity analyses were performed.

What was found

Twelve studies from ten countries were included (9 adequate quality, 3 good quality). The pooled relative risk (RR) for AMI following the spring transition was 1.04 (95% CI [1.02, 1.07], I² = 57.3%), and after the autumn transition was 1.02 (95% CI [0.99, 1.05], I² = 51.6%). After excluding one study with inconsistencies, the pooled RR in spring remained 1.04 (95% CI [1.01, 1.06], I² = 56.9%), while the autumn RR was 1.00 (95% CI [0.99, 1.02], I² = 17.1%).

Why it matters

This updated meta-analysis suggests a small, statistically significant increase in acute myocardial infarction risk immediately following the spring clock change, with no clear effect observed during the autumn transition.

Limits

All included data derive from observational designs prone to residual confounding. There was moderate heterogeneity among spring transition studies that persisted in sensitivity analysis, and total individual participant counts and absolute risk increases were not reported in the abstract.

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