Hasler · Neurogastroenterology and motility 2025 · narrative review · n=?

Cannabis use patterns and association with hyperemesis: A comprehensive review.

Cited 16 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review without systematic search or meta-analysis

PubMed 39164887 · doi:10.1111/nmo.14895 · record verified 2026-08-31

What was done

This narrative review synthesized literature on cannabis use patterns in the United States, clinical characteristics of cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS), diagnostic distinctions, and management strategies.

What was found

Forty to eighty percent of CVS patients report using cannabis products to alleviate nausea, vomiting, and stress. CHS is associated with longstanding, high-dose cannabis use, with most patients reporting daily or near-daily use for more than 2 years. Compulsive hot-water bathing is reported by most CHS patients, but is not specific to the condition as it also occurs in about half of CVS patients. Cannabis abstinence is the primary management strategy for CHS. The abstract provides no other quantitative metrics.

Why it matters

With increasing availability of high-potency cannabis, distinguishing CHS from CVS is essential for preventing recurrent healthcare utilization and focusing treatment on sustained cannabis cessation.

Limits

This is a narrative review rather than a systematic review, with no search methodology, inclusion criteria, or total participant sample size reported in the abstract. Quantitative data on cessation success rates and long-term outcomes were not provided.

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