Oral microbiome in human health and diseases.
Level 5 - mechanism / opinion, no new human data
Narrative review synthesizing mechanisms and associations without new primary data or quantitative meta-analysis.
PubMed 39359681 · doi:10.1002/mlf2.12136
What was done
The authors reviewed published literature on the composition, site-specific niche diversity, and regulation of the oral microbiome, as well as its links to local and systemic diseases.
What was found
The abstract reports no quantitative data or specific numerical results. It qualitatively describes bidirectional associations between oral microbiota dysbiosis and various systemic conditions, including cardiovascular disease, respiratory disease, and cancer.
Why it matters
It provides an overview of oral microbial ecology across distinct anatomical niches, highlighting potential pathways connecting oral dysbiosis to systemic health outcomes.
Limits
The abstract does not report search methodology, inclusion criteria, sample sizes, or quantitative effect estimates. It primarily addresses associative links rather than demonstrating definitive causality.
Cited by
- supports The oral microbiome is second only to the gut microbiome in both diversity and size within the human body.