Towards personalized vaccines.
Level 5 - mechanism / opinion, no new human data
Narrative review without systematic search methodology or primary empirical data
PubMed 39421749 · doi:10.3389/fimmu.2024.1436108
What was done
Conceptual narrative review exploring the integration of vaccinomics, systems vaccinology, genomics, transcriptomics, proteomics, and immunology to support personalized vaccine strategies.
What was found
The abstract reports no numerical findings, primary trials, or quantitative measurements. It describes the conceptual potential of personalized vaccines to enhance efficacy and safety alongside technical, economic, ethical, and regulatory challenges.
Why it matters
Synthesizes the theoretical transition from population-level vaccination strategies toward precision medicine approaches tailored to individual genetic and immune profiles.
Limits
The abstract provides no primary human empirical data, clinical trial outcomes, or systematic literature search. High-level conceptual review without quantitative validation of personalized vaccine efficacy, costs, or scalability.
Cited by
- supports Mayo Clinic leads the field of vaccinomics, studying how genetic and immune differences affect individual responses to vaccines.