Magnesium Matters: A Comprehensive Review of Its Vital Role in Health and Diseases.
Level 5 - mechanism / opinion, no new human data
Narrative review synthesizing secondary literature without primary data or systematic review methodology
PubMed 39539878 · doi:10.7759/cureus.71392
What was done
This was a narrative review examining the physiological roles of magnesium, its dietary sources, and the health implications of magnesium deficiency or insufficiency based on existing literature.
What was found
The abstract reports no primary quantitative data or effect sizes. It describes magnesium as a cofactor for over 300 enzymatic reactions and summarizes general associations between inadequate magnesium levels and chronic conditions such as hypertension, type 2 diabetes, osteoporosis, and cardiovascular diseases.
Why it matters
The paper provides a broad overview of the mechanistic and epidemiological literature linking dietary magnesium to cardiometabolic and musculoskeletal health.
Limits
As a narrative review, it lacks a systematic search protocol, study quality grading, quantitative synthesis, and original empirical data.
Cited by
- supports Magnesium acts as an essential cofactor for over 300 different enzymatic reactions in the human body and is required for DNA repair.