Zaidel · Handbook of clinical neurology 2025 · narrative review · n=?

The arts and hemispheric specialization.

Cited 1 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review synthesizing lesion studies, neuroimaging data, and evolutionary perspectives without systematic review methodology.

PubMed 40074411 · doi:10.1016/B978-0-443-15646-5.00002-6 · record verified 2026-08-26

What was done

This narrative review synthesized historical and contemporary literature on cerebral lateralization and the arts, focusing on observations of artwork produced by professional artists after unilateral hemispheric damage, functional neuroimaging (fMRI) studies of aesthetic evaluation, and evolutionary timelines relating cerebral asymmetry to art production.

What was found

The abstract reports no numerical data. It finds that quality artwork can be produced following damage to either the left or right hemisphere, contrary to early theories of right-hemisphere dominance. Functional neuroimaging reveals widespread bilateral activation across both hemispheres during aesthetic evaluation. Artistic production, aesthetic appreciation, creativity, and imagination are supported by complementary interhemispheric networks. Additionally, fossil evidence of cerebral asymmetry in early Homo sapiens predates consistent, abundant visual art production by hundreds of thousands of years.

Why it matters

It counters the persistent neuromyth of right-hemisphere exclusivity for artistic ability by showing that art and creativity require complex bi-hemispheric cooperation.

Limits

As a narrative review, it lacks systematic search criteria, explicit inclusion/exclusion criteria, and quantitative synthesis. Specific sample sizes, effect sizes, and specific clinical lesion characteristics are not reported in the abstract.

Cited by