Meixner · Translational sports medicine 2025 · cross-sectional physiological study · n=50

Zone 2 Intensity: A Critical Comparison of Individual Variability in Different Submaximal Exercise Intensity Boundaries.

Cited 9 times in the scientific literature.

Level 4 - case-series / case-control

Cross-sectional physiological study evaluating measurement variability across exercise testing markers in a single cohort

PubMed 40225831 · doi:10.1155/tsm2/2008291 · record verified 2026-08-29

What was done

Fifty cyclists (30 males, 20 females) completed laboratory incremental ramp and step exercise tests. Researchers measured power output, heart rate, blood lactate, ventilation, and substrate utilization to evaluate intra- and interindividual variability among commonly used Zone 2 (Z2) intensity boundaries.

What was found

Coefficients of variation (CV) across Z2 intensity markers ranged from 6% to 29%. Ventilatory Threshold 1 (VT1) and maximal fat oxidation (Fat Max) showed strong alignment, whereas fixed percentages of maximum heart rate (HRmax) and blood lactate thresholds exhibited wide individual differences.

Why it matters

Standardized Zone 2 prescriptions based on fixed percentages of maximum heart rate often misalign with actual metabolic status, supporting individualized physiological testing (such as VT1 or Fat Max) to accurately target low-intensity endurance zones.

Limits

The study was confined to 50 cyclists in a laboratory setting, limiting generalizability to other endurance disciplines or broader populations. The abstract reports CV ranges (6%–29%) but omits exact threshold values, specific metric-by-metric CV figures, and statistical dispersion metrics. Longitudinal training adaptation outcomes from personalized versus fixed prescriptions were not evaluated.

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