Evaluating the Role of Coenzyme Q10 in Migraine Therapy-A Narrative Review.
Level 5 - mechanism / opinion, no new human data
Narrative review without systematic methodology or quantitative synthesis
PubMed 40227290 · doi:10.3390/antiox14030318
What was done
Narrative review evaluating published literature on the role of coenzyme Q10 (CoQ10) supplementation as an adjunct for migraine treatment and prevention.
What was found
The abstract provides no numerical findings, effect estimates, or dose specifics. It qualitatively reports that CoQ10 supplementation across various doses was associated with reductions in migraine attack frequency, duration, pain intensity, days with migraine, and nausea, mediated by anti-inflammatory, antioxidant, and mitochondrial energy mechanisms.
Why it matters
Summarizes the rationale for CoQ10 as an accessible, non-pharmacologic adjunctive strategy for migraine prophylaxis.
Limits
As a narrative review, it lacks a systematic search protocol, risk of bias assessment, and meta-analytic pooling. The abstract lacks all quantitative data, sample sizes, and safety outcomes.
Cited by
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