Yılmaz · BMC sports science, medicine & rehabilitation 2025 · within-subject crossover trial · n=17

Voluntary hyperventilation-induced hypocapnia enhances wingate test performance without altering energy system contributions.

Cited 1 times in the scientific literature.

Level 3 - non-randomized controlled study

Controlled within-subject crossover study without stated randomization in the abstract

PubMed 40604959 · doi:10.1186/s13102-025-01217-z · record verified 2026-08-30

What was done

Seventeen male team-sport athletes completed 30-second Wingate anaerobic tests under two conditions separated by 2 to 3 days: control and pre-exercise voluntary hyperventilation (5 minutes of controlled breathing at 1000 mL tidal volume and 30 breaths·min⁻¹ to induce hypocapnia). Investigators measured peak power, mean power, blood lactate accumulation via capillary samples, and relative energy system contributions (oxidative, glycolytic, ATP-PCr) using breath-by-breath gas analysis.

What was found

Pre-exercise hyperventilation significantly increased relative peak power (12.7 ± 1.55 vs. 11.9 ± 1.05 W·kg⁻¹, p = 0.007) and mean power (9.0 ± 0.65 vs. 8.6 ± 0.67 W·kg⁻¹, p = 0.005) compared to control. No significant differences were observed between hyperventilation and control for oxidative contribution (20.1 ± 3.9% vs. 20.4 ± 2.3%), glycolytic contribution (41.1 ± 4.7% vs. 41.4 ± 3.7%), ATP-PCr contribution (38.9 ± 5.5% vs. 38.4 ± 4.2%), total energy expenditure, or blood lactate accumulation (12.6 ± 1.9 vs. 12.8 ± 1.2 mmol·L⁻¹).

Why it matters

Inducing hypocapnia via acute voluntary hyperventilation provides an endogenous strategy that modestly improves sprint cycling power output without altering macro-level metabolic pathway contributions.

Limits

The study had a small sample size (n = 17) limited to male team-sport athletes. The abstract does not mention whether condition order was randomized or counterbalanced, and proposed physiological mechanisms such as improved buffering or neuromuscular activation were not directly measured.

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