From traditional Chinese medicine to molecular oncology - pleiotropic effects of tauroursodeoxycholic acid.
Level 5 - mechanism / opinion, no new human data
Narrative review summarizing existing literature without primary empirical data or systematic synthesis
PubMed 40962506 · doi:10.48095/ccko2025270
What was done
The authors synthesized literature on the biological properties and therapeutic potential of tauroursodeoxycholic acid (TUDCA), a hydrophilic secondary bile acid, across hepatobiliary and extrahepatic clinical domains.
What was found
The abstract provides no numerical findings, effect sizes, or statistical metrics. It qualitatively notes that TUDCA demonstrates multifunctional properties with potential utility in oncology, neurodegenerative conditions, cardiovascular disease, gastrointestinal dysfunction, and glucose metabolism disorders.
Why it matters
This review highlights the expanding interest in repurposing TUDCA beyond traditional hepatology indications toward systemic and oncological applications.
Limits
The abstract describes a narrative overview without detailing search methodology, inclusion criteria, or risk of bias assessments. No primary human clinical trial data or quantitative results are reported.
Cited by
- supports TUDCA thins bile, promotes bile flow, and acts as an antibacterial disinfectant in the small intestine.