Porges · Frontiers in behavioral neuroscience 2025 · narrative review and theoretical perspective · n=?

Polyvagal theory: a journey from physiological observation to neural innervation and clinical insight.

Cited 18 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review and theoretical synthesis without original empirical data or systematic search

PubMed 41035859 · doi:10.3389/fnbeh.2025.1659083 · record verified 2026-08-28

What was done

This is a theoretical review and perspective article that synthesizes the scientific foundations of Polyvagal Theory (PVT) with recent developments in transcriptomics, neurophysiology, and clinical application. The paper reviews the hierarchical model of the autonomic nervous system, the role of the ventral vagal complex in social behavior, and the construct of neuroception, while addressing critiques and providing a narrative on the theory's origin.

What was found

The abstract reports no quantitative data, sample numbers, or statistical findings. It provides a theoretical synthesis and conceptual discussion of Polyvagal Theory and its translational role in mental health and clinical therapy.

Why it matters

The article provides an updated conceptual overview of Polyvagal Theory in response to critiques and recent biological literature, explaining how autonomic regulation frameworks are framed for clinical practice.

Limits

This paper is a narrative theoretical review and perspective containing no original empirical data, quantitative measurements, or systematic review methodology.

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