Nutritional Interventions for Enhancing Sleep Quality: The Role of Diet and Key Nutrients in Regulating Sleep Patterns and Disorders.
Level 5 - mechanism / opinion, no new human data
Narrative review synthesizing clinical trials, observational studies, and mechanistic research without systematic review methodology.
PubMed 41356231 · doi:10.1002/fsn3.71309
What was done
The authors conducted a review synthesizing literature from the past two decades on nutritional interventions for sleep regulation. The synthesis covered specific nutrients (e.g., magnesium, tryptophan, omega-3 fatty acids), dietary patterns (Mediterranean, ketogenic, plant-based), chrononutrition, functional foods, gut microbiome modulation via probiotics and prebiotics, and personalized nutrition frameworks across clinical trials, observational studies, and mechanistic research.
What was found
The abstract reports no numerical values, effect sizes, or confidence intervals. It qualitatively reports that anti-inflammatory and antioxidant dietary patterns, specific micronutrients, functional foods (tart cherry juice, kiwifruit), and microbiome-targeted interventions demonstrate potential benefits for sleep outcomes and sleep physiology regulation.
Why it matters
It aggregates diverse non-pharmacological, nutrition-based modalities for sleep support into a broad overview spanning single nutrients to whole-diet and microbiome approaches.
Limits
The review provides no quantitative data or meta-analytic pooling in the abstract. As a narrative review rather than a systematic review, it is susceptible to selection bias and aggregates heterogeneous study designs ranging from mechanistic work to clinical trials without standardized outcome grading.
Cited by
- supports Observational studies demonstrate that omega-3 fatty acid deficiency is correlated with poor sleep quality.