Edgar · Advances in dental research 1995 · narrative review · n=?

Role of saliva in caries models.

Cited 73 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review of mechanisms without original empirical data or systematic search methodology.

PubMed 8615945 · doi:10.1177/08959374950090030701 · record verified 2026-08-28

What was done

This narrative review describes the protective role of saliva in maintaining the balance between demineralization and remineralization in caries development. It outlines static and dynamic salivary effects and evaluates how experimental caries models must account for these physiological mechanisms.

What was found

No quantitative data or sample numbers are reported in the abstract. Salivary buffering of plaque acids and sugar clearance are highlighted as key dynamic mechanisms preventing demineralization, while saliva and fluoride act cooperatively to facilitate remineralization of white spot lesions.

Why it matters

The paper provides a conceptual framework for understanding salivary defenses in cariology and emphasizes that caries models must properly incorporate salivary actions to produce valid experimental findings.

Limits

The paper is a narrative overview without primary human data, sample sizes, or systematic review methodology. The abstract notes that the relative importance of specific protective properties of saliva remains uncertain.

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