Kiecolt-Glaser · Journal of consulting and clinical psychology 1996 · cross-sectional observational study · n=90 couples

Marital conflict and endocrine function: are men really more physiologically affected than women?

Level 4 - case-series / case-control

Cross-sectional observational study evaluating physiological associations with observed marital behaviors.

PubMed 8871417 · doi:10.1037//0022-006x.64.2.324 · record verified 2026-08-26

What was done

The study assessed marital conflict behavior and endocrine function in 90 newlywed couples. Blood samples collected hourly from 8:00 a.m. through 10:00 p.m. were combined into composite daytime values for three stress hormones (epinephrine, norepinephrine, and cortisol) and three related hormones (ACTH, growth hormone, and prolactin) on a day that included conflict.

What was found

No numerical values, effect sizes, or test statistics are reported in the abstract. Directionally, higher probabilities of husband withdrawal following wife negative behavior were associated with higher norepinephrine and cortisol levels in wives. Higher frequencies of positive behaviors were associated with lower epinephrine and higher prolactin levels in wives. Husbands' endocrine data were not associated with behavioral data.

Why it matters

The findings suggest that neuroendocrine responses to marital conflict differ by sex, with wives demonstrating greater physiological reactivity to demand-withdrawal interaction patterns.

Limits

The sample was restricted to 90 newlywed couples, limiting generalizability to other relationship durations or clinical populations. No specific quantitative data or effect sizes are provided in the abstract, and the observational design cannot establish causality.

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