Greenstein · Journal of periodontology 1997 · narrative review · n=?

Bacterial transmission in periodontal diseases: a critical review.

Cited 82 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review of observational molecular tracking studies without systematic review methodology

PubMed 9182736 · doi:10.1902/jop.1997.68.5.421 · record verified 2026-08-28

What was done

This paper is a critical narrative review evaluating evidence on intra-familial and extra-familial transmission routes of bacteria associated with periodontal disease, focusing on evidence from molecular genetic differentiation techniques and the role of saliva as a transmission vector.

What was found

The abstract reports no numerical data, sample sizes, or statistical estimates. Qualitatively, it notes strong evidence for parent-to-child bacterial transmission (colonized children typically harbor genotypically identical strains to a parent) and less frequent transfer between spouses. Bacterial transfer via saliva does not consistently result in host colonization, infection, or clinical disease, likely due to host defenses, bacterial antagonism, or variable bacterial pathogenicity.

Why it matters

The review synthesizes evidence showing that while periodontal pathogens are communicable—predominantly between parents and children—they are not readily transmissible or sufficient on their own to cause clinical disease.

Limits

The abstract provides no quantitative metrics, search parameters, or study selection criteria. As a narrative review published in 1997, it lacks formal systematic methodology and reflects only early molecular tracking literature.

Cited by