Initial sequencing and analysis of the human genome
Level 5 - mechanism / opinion, no new human data
Descriptive laboratory genomic resource paper without clinical trial design (graded Level 5 by design analogy).
OpenAlex W2168909179 · doi:10.1038/35057062
What was done
An international collaboration generated and made freely available a draft sequence of the human genome, accompanied by an initial descriptive analysis of the data.
What was found
The abstract reports no numerical values, coverage statistics, gene counts, or specific comparative data, stating only that a draft sequence was produced and that initial insights were derived regarding human development, physiology, medicine, and evolution.
Why it matters
This publication provided the initial open-access reference draft of the human genome to the scientific community.
Limits
The abstract provides no information regarding donor sample size, sequencing depth, error rates, assembly completeness, or technical methodology. As an initial draft, the sequence is by definition incomplete.
Cited by
- supports A draft of the human genome was completed around 2000 through an international multi-billion-dollar effort.