Roni L. Moya · Integrative Food Nutrition and Metabolism 2017 · narrative review · n=?

Brain nutrition-orthomolecular aspects

Cited 0 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative mini-review discussing mechanisms without systematic search methodology or original clinical data.

OpenAlex W2793885127 · doi:10.15761/ifnm.1000188 · record verified 2026-08-28

What was done

This mini-review summarized theoretical concepts and mechanisms at the intersection of neuroscience, anti-aging medicine, and orthomolecular medicine (using Linus Pauling's framework) regarding neurogenesis, neuroplasticity, and age-related neurological decline.

What was found

The abstract reports no empirical data, statistical analyses, or quantitative findings. It presents conceptual overviews linking factors such as dietary antioxidants, caloric restriction, mindfulness, sleep, exercise, and hormonal regulation to cellular maintenance mechanisms (e.g., DNA repair, neurotrophin release, mitochondrial regulation, and apoptosis control).

Why it matters

It outlines a broad framework of lifestyle and orthomolecular nutritional approaches hypothesized to support neuroplasticity in aging brains.

Limits

The abstract describes a non-systematic narrative mini-review with no primary clinical or experimental data, no quantitative outcomes, and no methodological details regarding literature selection.

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