Ronnie Levin · Journal of Exposure Science & Environmental Epidemiology 2023 · narrative review · n=?

US drinking water quality: exposure risk profiles for seven legacy and emerging contaminants

Cited 165 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review synthesizing contaminant profiles and regulatory challenges without systematic search methodology.

OpenAlex W4386955528 · doi:10.1038/s41370-023-00597-z · record verified 2026-08-26

What was done

The authors conducted a narrative review summarizing exposure risk profiles and health effects for seven legacy and emerging US drinking water contaminants: arsenic, disinfection by-products, fracking-related substances, lead, nitrate, per- and polyfluoroalkyl substances (PFAS), and uranium. The review also examined US public water system structures, regulatory frameworks, and systemic vulnerabilities including aging infrastructure, climate change, child-care settings, and health disparities affecting Indigenous and marginalized communities.

What was found

The abstract reports no quantitative values or statistical effect sizes. It reports qualitative findings that exposure profiles, health risks, and water reliability vary widely across US populations and regions depending on water source, local geography, infrastructure deterioration, industrial activity, and social determinants.

Why it matters

This review compiles multi-contaminant health risks alongside structural and regulatory challenges to outline priorities for water quality mitigation and public health interventions across US drinking water systems.

Limits

The abstract provides no quantitative data, search syntax, inclusion/exclusion criteria, or study counts. As a narrative review, it is prone to selection bias and provides descriptive synthesis rather than systematic risk quantification.

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