Before the measles vaccine was introduced, measles caused a couple hundred deaths annually in the United States.
"I mean, you're talking even measles before the vaccine, you had a couple, you know, a couple hundred deaths a year, lots of cases, but but still not as many deaths." (said at 0:40:05)
No published record matching the claim that measles caused a couple hundred deaths annually in the United States prior to the introduction of the measles vaccine was located; this does not prove the claim false.
corroborated by web sources
According to the Centers for Disease Control and Prevention, in the decade before the first measles vaccine was licensed in 1963, an estimated 400 to 500 people died from measles annually in the United States.