FoundMyFitness · 2019-06-10 · Rhonda Patrick (host), Elissa Epel
Dr. Elissa Epel on Telomeres and the Role of Stress Biology in Cellular Aging
46 claims checked against research: 2 contradicted 3 overstated 3 needing context 35 supported 1 corroborated online 2 unverified
2 No source found (not proven false)
Perseverative cognition and waking stress in caregivers correlate with elevated cortisol and accelerated aging biomarkers like inflammation and shorter telomere length.
"And we are looking at daily stress in our current studies and seeing that people who have this profile of more elevated—we call it perseverative cognition or thought processes—they have accelerated biomarkers of aging: telomere length and inflammation... We find that our caregivers do that a lot more. They wake up, they are already in a stressed state, their cortisol is higher." (said at 0:26:44)
No published record matching the claim that perseverative cognition and waking stress in caregivers correlate with elevated cortisol and accelerated aging biomarkers such as inflammation and shorter telomere length was located; this does not prove the claim false.
In cellular and mouse models, estrogen upregulates telomerase, enhances mitochondrial ATP production, and reduces oxidative stress leakage.
"estrogen, when we look at these experimental models and in vitro and in mice, estrogen is protective and anti-aging in a sense in that it upregulates telomerase, it improves mitochondrial health. Those energy stores in our cells, those batteries, are more robust, they create more ATP, they leak less oxidative stress." (said at 0:31:12)
No published record matching the claim that estrogen upregulates telomerase, enhances mitochondrial ATP production, and reduces oxidative stress leakage in cellular and mouse models was located; this does not prove the claim false.
Unverified means no publication matching the claim was located; it does not prove the claim false. Spotted an error? See the corrections policy - disputes from the people quoted are prioritized.