Mark Hyman, MD · 2025-09-24 · Mark Hyman (host), Shebani Sethi

How To Use Metabolic Psychiatry To Heal Your Anxiety & Depression | Stanford Psychiatrist

31 research-tied claims examined: 1 contradicted 2 overstated 2 context 21 supported 5 unverified

5

No source found (not proven false)

0:00:04Shebani Sethiunverifiedvery low

Insulin resistance doubles the risk of developing depression, even in individuals with no psychiatric history.

"and that doubles your risk of developing depression even if you have had no psychiatric history." (said at 0:00:04)

No published record matching the claim that insulin resistance doubles the risk of developing depression in individuals with no psychiatric history was located; this does not prove the claim false.

0:33:55Mark Hyman (host)unverifiedvery low

Function Health data indicates that 70% of members have a nutritional deficiency below the minimum level recommended by the RDA.

"like with Function Health, we're seeing like 70% have a nutritional deficiency at the minimum level that's actually recommended by the RDA." (said at 0:33:55)

No published record matching the claim that internal data from Function Health shows 70% of members have a nutritional deficiency below Recommended Dietary Allowance (RDA) minimums was located; this does not prove the claim false. Function Health is a direct-to-consumer commercial health-testing company whose proprietary member dataset and internal testing metrics have not been published in peer-reviewed biomedical literature.

0:34:06Mark Hyman (host)unverifiedvery low

Function Health biomarker data indicates that 95% of members have metabolic dysfunction measured by lipid particle size and 46% have elevated C-reactive protein levels.

"We're seeing, you know, 95% with metabolic dysfunction through the lipid particle size, and we're seeing 46% with high CRPs, and we're seeing a lot of really significant inflammation." (said at 0:34:06)

No published record matching the claim that 95% of Function Health members have metabolic dysfunction based on lipid particle size and 46% have elevated C-reactive protein levels was located; this does not prove the claim false.

0:46:22Shebani Sethiunverifiedvery low

The United States Senate Appropriations Committee issued a recommendation directing the National Institute of Mental Health (NIMH) to fund research on nutritional science and nutritional ketosis for serious mental illness.

"the Senate Appropriations Committee came out with a recommendation for the NIMH to put more money and funding into—guess what—nutritional science or nutritional ketosis work in serious mental illness specifically." (said at 0:46:22)

No published record matching the claim that the United States Senate Appropriations Committee issued a recommendation directing the National Institute of Mental Health (NIMH) to fund research on nutritional science or nutritional ketosis in serious mental illness was located; this does not prove the claim false.

1:08:44Shebani Sethiunverifiedvery low

A 9-year-old pediatric patient presenting with severe aggression and disruptive behavior had elevated gut bacterial and fungal metabolites on a urine test and experienced rapid symptom resolution following treatment with an antibiotic, an antifungal, and probiotics.

"I remember this little girl I had who was a beautiful 9-year-old little girl who was just a terror, and she was kicked out of her class like routinely in school, on the bus ride home they'd have to stop the bus 15 times to deal with her disruptive behavior and violence, aggression. I did a urine test which looked at metabolites of bacteria and yeast in the gut, and she just was off the chart with fungal metabolites and bacterial metabolites. And so like, "I'm just going to go back to first principles and reset her gut and give her an antibiotic and an antifungal and give her some probiotics." It was like the lights just came on in this girl overnight. She went from like this terror to being this sweet little girl." (said at 1:08:44)

No published record matching this clinical case report—of a 9-year-old child presenting with severe behavioral disruption and aggression who was evaluated via urinary microbial metabolites and treated with an antibiotic, antifungal, and probiotics—was located; this does not prove the claim false.

Unverified means no publication matching the claim was located; it does not prove the claim false. Spotted an error? See the corrections policy - disputes from the people quoted are prioritized.