DavidPerlmutterMD · 2026-03-17 · David Perlmutter (host), Andrew Koutnik
The Fuel Myth: Rethinking Carbs, Brain Health, and Human Performance | Andrew Koutnik
46 research-tied claims examined: 1 contradicted 2 overstated 7 context 27 supported 3 corroborated online 6 unverified
3 Corroborated by web sources
William Sansum was the first person in the United States to chemically extract and administer insulin to save a patient's life.
"So, William Sansum, where I used to work, was actually the first person in the United States of America to both chemically extract and also administer insulin to save the life of a patient in the United States of America." (said at 0:28:40)
No published record matching the claim that William Sansum was the first person in the United States to chemically extract and administer insulin to save a patient's life was located; this does not prove the claim false.
corroborated by web sourcesHistorical and medical sources confirm that Dr. William Sansum was the first physician in the United States to successfully extract insulin in a laboratory and administer it to a patient, treating Charles Cowan on May 31, 1922.
sansum.orgphilanthropyroundtable.org
In 1925, William Sansum published a paper in JAMA advocating that patients receiving insulin should have enhanced dietary freedom, without support from randomized controlled trials.
"William Sansum the founder of the institute I worked at also published a paper in JAMA in 1925 where he then argued that patients with the ability to administer insulin should now have enhanced freedom in their dietary choices. He made this recommendation in the absence of any serious, rigorous, randomized control trial evidence." (said at 0:29:00)
No published record matching William Sansum's 1925 JAMA paper on enhanced dietary freedom for insulin-treated patients was located; this does not prove the claim false.
corroborated by web sourcesDr. William D. Sansum and colleagues published a landmark paper in JAMA (January 1926, detailing clinical work from 1925) advocating for more liberal carbohydrate diets in insulin-treated patients. As randomized controlled trials had not yet been introduced to medical research, his recommendations were based on observational clinical case series.
semanticscholar.orgmasteringdiabetes.org
In 1962, MIT studied 1,3-butanediol for aerospace transport as a shelf-stable, high-caloric-density nutrient.
"So, then in 1962, MIT actually studied 1,3-butanediol, which is in products like Ketone-IQ, for aerospace transport. Why were they interested in that? Because it was a very shelf-stable molecule that could go into outer space with high caloric density." (said at 0:50:20)
No published record matching the claim that MIT studied 1,3-butanediol in 1962 as a shelf-stable, high-caloric-density nutrient for aerospace transport was located; this does not prove the claim false.
corroborated by web sourcesIn the early 1960s, researchers at the Massachusetts Institute of Technology investigated synthetic energy sources for extended human spaceflight, identifying 1,3-butanediol as a promising shelf-stable, high-caloric-density nutrient.
nih.gov
Unverified means no publication matching the claim was located; it does not prove the claim false. Spotted an error? See the corrections policy - disputes from the people quoted are prioritized.