83 claims checked against research: 3 overstated 5 needing context 69 supported 6 unverified
"and it turns out that the Nrf2 pathway controls something between 3 and 5% of our cellular proteins, so it's very important." (said at 0:08:07)
No published record matching the claim that the Nrf2 pathway controls between 3% and 5% of human cellular proteins was located; this does not prove the claim false.
"HOST: Does sulforaphene also activate Nrf2? GUEST1: It does, but to a lesser degree than sulforaphane." (said at 0:11:51)
No published record matching the claim that sulforaphene activates Nrf2 to a lesser degree than sulforaphane was located; this does not prove the claim false. While both isothiocyanates have been shown individually in preclinical models to induce phase 2 detoxification enzymes and activate the Nrf2 antioxidant pathway, direct comparative studies quantifying their relative potency for Nrf2 activation were not identified.
"we've tested a product by Thorne, which is a medium- or large-sized supplement maker, and their product is called Crucera-SGS, but that only has glucoraphanin." (said at 0:32:38)
No published record matching the claim that Thorne manufactures a dietary supplement called Crucera-SGS containing glucoraphanin without myrosinase was located; this does not prove the claim false.
"there's no evidence to date that people who say they eat, you know, a pound of broccoli a day—that's a little bit of an exaggeration, but people who eat a lot of broccoli don't necessarily convert glucoraphanin better than people who don't eat much at all." (said at 0:37:14)
No published record matching the claim that individuals who regularly consume large amounts of broccoli do not exhibit higher conversion rates of glucoraphanin to sulforaphane compared to low consumers was located; this does not prove the claim false.
"we know that we see the metabolites of sulforaphane appear in the blood within 10 minutes of ingestion." (said at 2:05:53)
No published record matching the claim that metabolites of sulforaphane appear in human blood within 10 minutes following ingestion was located; this does not prove the claim false.
"What you're doing when you take sulforaphane is you're upregulating a bunch of enzymes, and those enzymes have a rather long—comparatively a rather long—half-life, meaning they don't lose their punch, they don't get deactivated or get broken down all that fast. And their half-lives are on the order of days, maybe even weeks for some of them, but certainly a few days is a reasonable guess for many of them." (said at 2:07:40)
No published record matching the claim that phase II detoxifying enzymes upregulated by sulforaphane through Nrf2 activation have biological half-lives on the order of days to weeks was located; this does not prove the claim false.