Mark Hyman, MD · 2025-09-03 · Mark Hyman (host), Nolan Williams
One Dose That Heals Addiction, PTSD, and Brain Injury | The Science of Ibogaine
42 research-tied claims examined: 5 overstated 3 context 30 supported 4 unverified
4 No source found (not proven false)
Ibogaine was placed on France's list of controlled substances in 1966.
"and then placed on the French version of the Controlled Substances Act in '66." (said at 0:25:11)
No published record matching the claim that ibogaine was placed on France's list of controlled substances in 1966 was located; this does not prove the claim false.
Ibogaine was listed on the French pharmaceutical formulary as a medication for approximately 36 years between the 1930s and 1966.
"why did the French think this was helpful for 36? ... to have a drug on the formulary for 36 years that, you know, wasn't doing anything for the French, it seems unlikely-- it's possible, but unlikely-- that that would have stuck around and been sold for 36 years." (said at 0:58:11)
No published record matching the claim that ibogaine was listed on the French pharmaceutical formulary as a medication for approximately 36 years between the 1930s and 1966 was located; this does not prove the claim false.
Follow-up data out to one year in special forces veterans treated with ibogaine shows that most participants maintain their clinical improvements.
"So we have data out to a year. It isn't published yet. It's kind of in review now, actually, and uh that looks really good. Uh most people hold it." (said at 1:05:45)
No published record matching one-year follow-up clinical outcome data for ibogaine treatment in Special Operations Forces veterans was located; this does not prove the claim false, as the speaker noted the one-year data was unpublished and under review. Published prospective observational studies in this population have reported significant improvements in functional disability, PTSD, depression, anxiety, and alcohol misuse maintained up to 1 month (Williams et al., Nature Medicine 2024) and 6 months (Davis et al., 2023, 2024) post-treatment.
As of the time of the discussion, no published studies had administered a standardized personality inventory to assess personality changes following ibogaine administration.
"nobody's done a personality inventory study with ibogaine." (said at 1:11:59)
No published record matching the claim that no studies had administered a standardized personality inventory to assess personality changes following ibogaine administration was located; this does not prove the claim false.
Unverified means no publication matching the claim was located; it does not prove the claim false. Spotted an error? See the corrections policy - disputes from the people quoted are prioritized.