Periorbital puffiness and bags under the eyes caused by sleep deprivation are directly due to the pooling and impaired clearance of lymphatic fluid.
"everybody has bags under their eyes and looks like when they are sleep deprived. They sleep for a night or two and it goes away. That's clearly accumulation of lymph. We we actually know that. That's just lymph fluid that's not being cleared, and it might not even be the brain's glymphatic clearance system. It's just there's a bunch of lymph pooling under your eyes." (said at 0:51:27)
No published scientific records directly verifying the claim that under-eye puffiness and bags caused by sleep deprivation are directly due to the pooling and impaired clearance of lymphatic fluid were located. While sleep deprivation is known to affect facial appearance (such as causing transient periorbital puffiness or dark circles), dermatological literature generally attributes transient infraorbital swelling and discoloration to multifactorial vascular and interstitial fluid dynamics (such as venous pooling in thin eyelid tissues) and gravitational redistribution, rather than confirmed isolated impairment of lymphatic clearance.