Optoceutics' 40 Hz light technology achieves a 94% adherence rate and produces significant improvements across metrics including mood, energy, focus, sleep, and memory.
"So, there is a company called Optoceutics. They've solved this problem with a patented technology that still gives you the 40 Hz light flashing, but through light that looks and feels quite normal. It's the device I actually have on my desk when I'm working, and that's why this company sees a 94% adherence rate and significant improvements across various metrics, including mood, energy, focus, sleep, and memory." (said at 0:22:23)
Optoceutics developed an invisible spectral flicker (ISF) light technology designed to entrain 40 Hz gamma oscillations with less visual discomfort than stroboscopic flicker. However, claims of proven significant improvements across mood, energy, focus, sleep, and memory overstate the published clinical evidence. In a small pilot randomized controlled trial of ISF in mild-to-moderate Alzheimer's disease (n=11), adherence was reported above 86.1% of intended treatment days, and cognitive and structural MRI outcomes showed only exploratory non-significant tendencies, with authors concluding that potential efficacy must be tested in larger trials. Larger efficacy trials in Alzheimer's disease and major depressive disorder remain in protocol or preliminary stages.
- partial: Safety, Feasibility, and Potential Clinical Efficacy of 40 Hz Invisible Spectral Flicker v… (Journal of Alzheimer's disease : JAD 2023)
"Adherence was above 86.1% of intended treatment days, with participants remaining in front of the device for >51.3 min (60 max) and directed gaze >34.9 min. Secondary outcomes of cognition indicate a tendency towards improvement in the active group compared to placebo (mean: -2.6/1.5, SD: 6.58/6.53, active/placebo) at week 6. Changes in hippocampal and ventricular volume also showed no tendency of improvement in the active group at week 6 compared to placebo." (abstract, results, passage verified)
pubmedfull study (doi)